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The same people who have complaining about masks througout this past year have been running there mouth about how the vaccine is gonna do something wacky in there body. What.THe.Heck. JUST GET VAXED take a hit of that madournie and continue your journey
LukasSchroederthis is so dumb lol, if someone has cancer, respiratory issues, a broken arm, etc and they get Covid and die, they died from
Covid. Covid made them die, especially if they would've continued living, even 2 months if they had not gotten the virus.
Thank god I don't have any of those things then. Now I'm immune from DEATH. Although sometimes I wish an asteroid would hit my fucking apartment while i'm sleeping
T.L."RrrRreeeeeeEEEEEEEEEeeeeeeeeeEEEEeeEEEeeEEEEEEE!!! Antivaxxer!!! Terrorist!! Why did you personally overthrow the government on Jan. 6th?"
Lmaoooo unfortunately this way of thinking is more prevalent then you’d think. Feel like I’ve heard all this word for word except for the “Reeeee” part 😂
c-friesLmaoooo unfortunately this way of thinking is more prevalent then you’d think. Feel like I’ve heard all this word for word except for the “Reeeee” part 😂
Covid was a giant nothingburger for me. I didn't change anything in my life other than what was mandated. Never worried about getting it. Kept doing all my normal stuff. Never tripped out at all. I watched the numbers every day because stats interest me. I never understood the unbridled, sheer panic. The numbers never warranted anything remotely close to the fear this thing caused.
I live in a state of almost 6M people, and the death rate is around 5-7 people, statewide, a day. All those people are in high-risk groups. The mask mandates are basically gone entirely here. Everyone in my circle is vaccinated.
Why would I get the vaccine? I have nothing against vaccines, or the covid vaccines. I just really don't see any compelling reason to get it.
SuspiciousFishI dont trust the fact that these vaccines are an experimental mRNA therapy drug that has not actually been approved by the FDA. For instance Moderna has been working on these drugs since 2010 but have not gotten a single drug FDA approved due to safety until COVID-19.
I mean, most drugs are either rejected due to lack of efficacy or safety reasons. The fact that mRNA drugs failed Phase I/II/III trials or were stopped due to safety concerns shouldn't surprise anyone. There really isn't any other way for a product to fail. When it comes to pharmaceutical products, there's something called a therapeutic window which is a point where a product (drug or biologic) can have a strong enough effect on the disease without causing any safety issues. When there isn't a strong enough effect, it fails due to lack of efficacy. If it creates an overly dangerous bodily response, it's rejected due to safety concerns.
When it comes to mRNA products, this window historically has been very hard to find. Like most injectable products, mRNA vaccines/treatments need to be coated in a protective layer as a means to prevent the body from destroying the desired proteins before they can reach their ultimate destination (in this case, immune cells). For years, companies involved in the mRNA space have been searching for technology that can find this therapeutic window. Companies had to change their target diseases to ones that required minimal protein to have an effect.
10 years is really nothing when it comes to new drug technology, especially one has complex as an mRNA product. Biologics are similarly complex products that can provide a nice comparison. TNF inhibitors (like Humira, Enbrel, etc.) were first discovered in the 1980s but did not come to market until the late 1990s/early 2000s. Zidovudine, the first ARV for HIV/AIDs was discovered in the 1960s but didn't come to market until the 1980s.
Hell, CRISPR Therapeutics is still years away from any sort of novel treatment and has been around almost as long as Moderna.
.MASSHOLE.I mean, most drugs are either rejected due to lack of efficacy or safety reasons. The fact that mRNA drugs failed Phase I/II/III trials or were stopped due to safety concerns shouldn't surprise anyone. There really isn't any other way for a product to fail. When it comes to pharmaceutical products, there's something called a therapeutic window which is a point where a product (drug or biologic) can have a strong enough effect on the disease without causing any safety issues. When there isn't a strong enough effect, it fails due to lack of efficacy. If it creates an overly dangerous bodily response, it's rejected due to safety concerns.
When it comes to mRNA products, this window historically has been very hard to find. Like most injectable products, mRNA vaccines/treatments need to be coated in a protective layer as a means to prevent the body from destroying the desired proteins before they can reach their ultimate destination (in this case, immune cells). For years, companies involved in the mRNA space have been searching for technology that can find this therapeutic window. Companies had to change their target diseases to ones that required minimal protein to have an effect.
10 years is really nothing when it comes to new drug technology, especially one has complex as an mRNA product. Biologics are similarly complex products that can provide a nice comparison. TNF inhibitors (like Humira, Enbrel, etc.) were first discovered in the 1980s but did not come to market until the late 1990s/early 2000s. Zidovudine, the first ARV for HIV/AIDs was discovered in the 1960s but didn't come to market until the 1980s.
Hell, CRISPR Therapeutics is still years away from any sort of novel treatment and has been around almost as long as Moderna.
I want to add that the J&J is not an mRNA vaccine. It's an adenovirus vector vaccine. This type of vaccine has been studied since like the 70s. Multiple Ebola vaccines where created using this same method and were approved for use (one by the FDA) even before covid came around.
JAHpowI want to add that the J&J is not an mRNA vaccine. It's an adenovirus vector vaccine. This type of vaccine has been studied since like the 70s. Multiple Ebola vaccines where created using this same method and were approved for use (one by the FDA) even before covid came around.
Oh yeah, I'm straight up ignoring the J&J (and AZN) because they're using a proven technology.
Yes, the both have clotting concerns, but they're vastly overstated. The J&J one is among women of birthing age, where traditional birth control pills elevate the risk of clotting, so for the vast majority of the population it's not an issue. The AZN one is similar in that it creates clotting issues, but there hasn't been as strong an indication towards a certain subset of the population. However, it's a 1-in-100,000 chance.
Anyone who thinks any single drug out there doesn't have life-threatening side effects is naive. NSAIDs, one of the most common medicines out there, kill over 16,000 Americans annually. I don't think many people avoid NSAIDs because they're afraid of the potential SAEs.
skeirmanCovid was a giant nothingburger for me. I didn't change anything in my life other than what was mandated. Never worried about getting it. Kept doing all my normal stuff. Never tripped out at all. I watched the numbers every day because stats interest me. I never understood the unbridled, sheer panic. The numbers never warranted anything remotely close to the fear this thing caused.
I live in a state of almost 6M people, and the death rate is around 5-7 people, statewide, a day. All those people are in high-risk groups. The mask mandates are basically gone entirely here. Everyone in my circle is vaccinated.
Why would I get the vaccine? I have nothing against vaccines, or the covid vaccines. I just really don't see any compelling reason to get it.
well for starters serious respiratory issues fucking suck, and its a good idea to get the vaccine because you could be one of the unlucky dudes who get a serious case of covid and have a machine do your breathing, the vaccine irrefutably helps your odds to stop that from happening, like all vaccines.
Second it was very serious for a lot of places, the reality is that our very good healthcare infrastructure managed to tumble by pretty well in a lot of the country, but that didnt happen for every state luckily, the fact that we only have just shy of 600,000 thousand deaths is pretty impressive considering all the BS that went down during the brunt of the pandemic. However in places where hospitals got flooded, it crippled lots of other medical needs. That's where the main problem lies, the longer the pandemic goes the more resources have to be allocated to it, making everyone's lives that much more inconvenienced.
**This post was edited on May 19th 2021 at 10:59:31pm
I wonder if I can hire an outside company to trace how many ppl I infect involuntarily as an unvaccinated white male. I could possibly be killing more
than .04% of ppl a day. Considering the new Covid deaths rates. I wouldn’t even know. How dare I neglect to let someone inject me with a needle to make myself
sick for a day. That doesn’t sound like poison at all. Just martyrdom. I am one with the herd. And the herd one with me.
Let us recall when obesity, cigarettes and alcohol killed 15 times more people annually than Covid ever did worldwide
zuesI wonder if I can hire an outside company to trace how many ppl I infect involuntarily as an unvaccinated white male. I could possibly be killing more
than .04% of ppl a day. Considering the new Covid deaths rates. I wouldn’t even know. How dare I neglect to let someone inject me with a needle to make myself
sick for a day. That doesn’t sound like poison at all. Just martyrdom. I am one with the herd. And the herd one with me.
Let us recall when obesity, cigarettes and alcohol killed 15 times more people annually than Covid ever did worldwide
I was just in a plane to Florida masks and all. The only problem was the 300 pound woman next to me took her mask off to eat some fattening cheeseburger.
I just found it sad how she’s worried about dying from Covid but really she’s just killing herself with food.
zuesI just found it sad how she’s worried about dying from Covid but really she’s just killing herself with food.
I'm gonna have to side with zues on this one. He may have some retarded political takes but he's right in this regard.
I find it ironic that the one definitive thing we've learned about the virus is that obesity is the overwhelming risk factor for getting severely sick and dying of the virus, yet everyone's giving out free donuts or a free cheeseburger to people who have gotten the vaccine. Like its great you're bribing fat people with food so they don't die from this one thing, but it wouldn't be nearly as big of an issue if they weren't fat fucks in the first place. Damn go offer a free salad or a free gym trial or something like that.
You should still get the vaccine tho
**This post was edited on May 20th 2021 at 6:48:58pm
hdubsI'm gonna have to side with zues on this one. He may have some retarded political takes but he's right in this regard.
I find it ironic that the one definitive thing we've learned about the virus is that obesity is the overwhelming risk factor for getting severely sick and dying of the virus, yet everyone's giving out free donuts or a free cheeseburger to people who have gotten the vaccine. Like its great you're bribing fat people with food so they don't die from this one thing, but it wouldn't be nearly as big of an issue if they weren't fat fucks in the first place. Damn go offer a free salad or a free gym trial or something like that.
You should still get the vaccine tho
**This post was edited on May 20th 2021 at 6:48:58pm
It’s odd how whenever I see a drug commercial there are always a ton of disclaimers at the end. “Dry mouth, internal bleeding, yellowing of skin, in rare cases even death”.... etc
why is there no disclaimer on these government commercials for “just get the vaccine it’s safe and free”. At the very least mention the fact that half the people are sick for 24 hours, very few women are getting blood clots, etc.... in my speculation infertility and possibly cancer could be long term effects of just pumping out a vaccine in 6 months.
like I’m going to trust the government with my health when the morons can’t even minimize the countries national debt, can’t bring gas prices down, and can do nothing about inflation which is the highest it’s been in since the 2008 housing crisis.
I mean, by this point we're how many millions of dosages in?
If there were near-term and common SAEs we'd have seen evidence of them. Most (vaccine) clinical trials are nowhere near the size of what we're seeing right now. Most vaccine SAEs occur within the near-term as well.
Polio- 1 in 2.4 million had the chance of being paralyzed by the vaccine due to the virus reverting to the wild type poliovirus. This occurred within 30 days of being dosed.
Yellow Fever- Children under 6 months of age have an increased risk of brain or spinal cord swelling (this is why it's recommended children under 6 months do not take it). Additionally, there's a risk of viscerotropic disease, which can manifest in multi-organ failure. It shows up within 3 days of being dosed.
Flu Vaccine- The only "common" SAE is GBS, but that occurs in about 1 in a million vaccines and is more likely to occur from getting the flu than from the vaccine. It shows up within a few months.
MMR- Like with many drugs, there's a chance of thrombocytopenia within 1-3 weeks, but sometimes up to 8 weeks after dosage.
The few concerns we've seen are with the adenovirus vaccines, and anyone with a medical background can tell you clotting can be caused by a LOT of different things. To say that there's a causal link is wrong.
And with regards to long-term concerns, we know adenovirus vaccines are EXTREMELY safe. There's no doubting that. With regards to mRNA vaccines, we've seen data from animal, Phase I, and Phase II studies all of which SHOULD have shown any SAE over the long-term. Generally, when studies end, companies continue to follow up with patients to keep an eye on their health.
zuesI was just in a plane to Florida masks and all. The only problem was the 300 pound woman next to me took her mask off to eat some fattening cheeseburger.
I just found it sad how she’s worried about dying from Covid but really she’s just killing herself with food.
.MASSHOLE.I mean, by this point we're how many millions of dosages in?
If there were near-term and common SAEs we'd have seen evidence of them. Most (vaccine) clinical trials are nowhere near the size of what we're seeing right now. Most vaccine SAEs occur within the near-term as well.
Polio- 1 in 2.4 million had the chance of being paralyzed by the vaccine due to the virus reverting to the wild type poliovirus. This occurred within 30 days of being dosed.
Yellow Fever- Children under 6 months of age have an increased risk of brain or spinal cord swelling (this is why it's recommended children under 6 months do not take it). Additionally, there's a risk of viscerotropic disease, which can manifest in multi-organ failure. It shows up within 3 days of being dosed.
Flu Vaccine- The only "common" SAE is GBS, but that occurs in about 1 in a million vaccines and is more likely to occur from getting the flu than from the vaccine. It shows up within a few months.
MMR- Like with many drugs, there's a chance of thrombocytopenia within 1-3 weeks, but sometimes up to 8 weeks after dosage.
The few concerns we've seen are with the adenovirus vaccines, and anyone with a medical background can tell you clotting can be caused by a LOT of different things. To say that there's a causal link is wrong.
And with regards to long-term concerns, we know adenovirus vaccines are EXTREMELY safe. There's no doubting that. With regards to mRNA vaccines, we've seen data from animal, Phase I, and Phase II studies all of which SHOULD have shown any SAE over the long-term. Generally, when studies end, companies continue to follow up with patients to keep an eye on their health.
Nah brother, we are not aware of the effects the vaccine will have 70 years from now
I’m pro vaccine since all my family is medical and brother is ICU nurse in a major city hospital and lost 8 people in one day at work.
but for some, it’s also a matter of thinking others need it more. I’m a stay at home dad, i rarely leave, but saw how frustrating it was waiting for wife’s family to get it, most of the world needs vaccines, other people need it more.
Ever listen to bill burrs comedy? He does a bit about a fat fella next to him on a plane, listen to it if ya need a laugh, goes down good with some beer or a blunt, easy to find on YT
zuesI was just in a plane to Florida masks and all. The only problem was the 300 pound woman next to me took her mask off to eat some fattening cheeseburger.
I just found it sad how she’s worried about dying from Covid but really she’s just killing herself with food.
First it was there's no data so I'll wait. Then it's microchips. Then it's cancer, even though there's literally no possibility of this based on the mechanism; I could explain but you wouldn't understand. Then a totally different type of vaccine causes clots; that's 0.0025% of vaccine recipients of the AZN vaccine. Nothing for the mrna ones but people still use that as an excuse.
Lastly, this is 100% political. Look at the distribution across states and rural areas.
Literally every reason for not getting the vaccine has been disputed with evidence so we shouldn't even be having this conversation.
HypeBeastFirst it was there's no data so I'll wait. Then it's microchips. Then it's cancer, even though there's literally no possibility of this based on the mechanism; I could explain but you wouldn't understand. Then a totally different type of vaccine causes clots; that's 0.0025% of vaccine recipients of the AZN vaccine. Nothing for the mrna ones but people still use that as an excuse.
Lastly, this is 100% political. Look at the distribution across states and rural areas.
Literally every reason for not getting the vaccine has been disputed with evidence so we shouldn't even be having this conversation.
Now that 120 million Americans have been vaccinated. Why can they not donate their blood ? Sounds like that might cause a shortage
HypeBeastFirst it was there's no data so I'll wait. Then it's microchips. Then it's cancer, even though there's literally no possibility of this based on the mechanism; I could explain but you wouldn't understand. Then a totally different type of vaccine causes clots; that's 0.0025% of vaccine recipients of the AZN vaccine. Nothing for the mrna ones but people still use that as an excuse.
Lastly, this is 100% political. Look at the distribution across states and rural areas.
Literally every reason for not getting the vaccine has been disputed with evidence so we shouldn't even be having this conversation.
No I’m pretty sure the main factor to not get vaccinated is the 99.96% survival rate.
Bahahahaha. I’m a Betting man and I REALLY like those odds.
just to think that people are still scared of this virus that’s literally just the flu is fucking hilarious.
If everyone doesnt get the covid vaccine right now. A new more dominant strain will becime vaccine resistant. And we will have to start all over again.
zuesThe Red Cross isn’t accepting blood from vaccinated individuals. But it looks like that might be fake news.
That misinformed.
”In most cases, there is no deferral time for individuals who received a COVID-19 vaccine as long as they are symptom free and feeling well at the time of donation. The following eligibility guidelines apply to each COVID-19 vaccine received, including boosters” -Red Cross https://www.redcrossblood.org/donate-blood/dlp/coronavirus--covid-19--and-blood-donation.html
Jesus christ how bout you make sure you're posting accurate information. Congratulations Zeus. You just disseminatated misinformation with confidence. You can donate blood. There is a shortage and it's worse this year but not because of the vaccine.
zuesNow that 120 million Americans have been vaccinated. Why can they not donate their blood ? Sounds like that might cause a shortage
zuesNo I’m pretty sure the main factor to not get vaccinated is the 99.96% survival rate.
Bahahahaha. I’m a Betting man and I REALLY like those odds.
just to think that people are still scared of this virus that’s literally just the flu is fucking hilarious.
If any reason, get it so you can help prevent another outbreak cuz we all know how well that went. But you should also stop focusing on just mortality. The morbidity has taken quite its toll. It you still think this virus is a joke, ehhhhh you can't be helped. Do it for the children Zeus!
But seriously this isn't the flu. It's more deadly. And the morbidity is much much worse. The media focuses on morbidity and when hospitals are overwhelmed but they really don't focus too much on the people who survive and all the interventions that had to be made so they did survive. They don't even mention all the kids in the hospital with MIS-C, which can be quite severe; I've seen many kids come in with misc who present looking like severe septic shock but it's not sepsis-would have died in hours if they didn't get immediate care. Some of those patients will have permanent damage to various organs affecting the rest of their lives. The media doesn't talk about all the people who get admitted, put on vents, and then come off them and go home once they're better enough to be discharged. Going on a vent is bad news bears. So please for the love of God stop quoting mortality or calling it the flu as a rationale for saying covid isn't bad. Nearly 1 million Americans have died from covid; 36k die from influenza on average.....I've seen more non-elderly patients put on vents this year for covid than I probably will the rest of my life for influenza.
zuesThe Red Cross isn’t accepting blood from vaccinated individuals. But it looks like that might be fake news.
🤭 Moron.
This is the last I'm gonna post in this thread cuz I knew it would turn to this shit. But if you keep posting wrong facts, I'll be right here to contradict you.
I think what you mean is that nearly one million obese smokers who don’t take care of themselves died from being unhealthy. Covid just helped to speed it up.
we need more plague
HypeBeastJesus christ how bout you make sure you're posting accurate information. Congratulations Zeus. You just disseminatated misinformation with confidence. You can donate blood. There is a shortage and it's worse this year but not because of the vaccine.
If any reason, get it so you can help prevent another outbreak cuz we all know how well that went. But you should also stop focusing on just mortality. The morbidity has taken quite its toll. It you still think this virus is a joke, ehhhhh you can't be helped. Do it for the children Zeus!
But seriously this isn't the flu. It's more deadly. And the morbidity is much much worse. The media focuses on morbidity and when hospitals are overwhelmed but they really don't focus too much on the people who survive and all the interventions that had to be made so they did survive. They don't even mention all the kids in the hospital with MIS-C, which can be quite severe; I've seen many kids come in with misc who present looking like severe septic shock but it's not sepsis-would have died in hours if they didn't get immediate care. Some of those patients will have permanent damage to various organs affecting the rest of their lives. The media doesn't talk about all the people who get admitted, put on vents, and then come off them and go home once they're better enough to be discharged. Going on a vent is bad news bears. So please for the love of God stop quoting mortality or calling it the flu as a rationale for saying covid isn't bad. Nearly 1 million Americans have died from covid; 36k die from influenza on average.....I've seen more non-elderly patients put on vents this year for covid than I probably will the rest of my life for influenza.
🤭 Moron.
This is the last I'm gonna post in this thread cuz I knew it would turn to this shit. But if you keep posting wrong facts, I'll be right here to contradict you.
zuesI think what you mean is that nearly one million obese smokers who don’t take care of themselves died from being unhealthy. Covid just helped to speed it up.
zuesI think what you mean is that nearly one million obese smokers who don’t take care of themselves died from being unhealthy. Covid just helped to speed it up.
zuesI think what you mean is that nearly one million obese smokers who don’t take care of themselves died from being unhealthy. Covid just helped to speed it up.
we need more plague
No sense arguing with a wall but there's plenty of previously healthy people especially children, who now have permanent damage from covid. You don't hear about that because you're focused on mortality.
But yes America is fat as fuck. Our next generation is gonna be even fatter. That's an issue. A huge issue. Obesity is literally a risk factor for everything bad. Cardiovascular disease is an issue. Preventable cancers are an issue. Traumatic injury deaths are usually preventable. Type 2 diabetes is laughable how common it is and if you know anything about its causes and what persistent hyperglycemia does to the body, you would see this as hilariously preventable too.
But people don't care about the future. They can't rationalize what their actions now will do 10, 20, 30 years down the road. Try managing a Type 2 diabetic's care and see how much effort it takes and they still aren't adherent to their meds. Covid is now. That's why it gets so much focus. Because it's easily preventable and causes immediate effects as well as permanent disability.
I'll agree that it's a drop in the bucket to poor health but it's still notable when it becomes the leading cause of death in America, especially when it outpaced cardiovascular disease and cancer combined last fall/early winter. So take it seriously as we do with all other diseases.
Cancer isn't common in young people either but we still worry about getting it in the future... let that sink in.
I could rant all day about how covid is nothing compared to other healthcare issues. That true. But it's also easily prevented so our actions can have major impacts and should be done.
Technically Zeus is right though. It's natural selection. It's a great purge for those unhealthy and old and draining on society. Wohoo. On the other hand. How many of you wouldn't be here if we just let natural selection play out? I'd gander >50% of us would be dead by now.
So your saying there’s hope, hope that traffic, will return to the way it was last spring.... nice
b0ssIf everyone doesnt get the covid vaccine right now. A new more dominant strain will becime vaccine resistant. And we will have to start all over again.
I do, saved me considerable time and considerable payroll since guys weren’t sitting in traffic, all my drivers were in lot better moods, plus the ghost town feeling, I kinda liked it
zueslmao. My thoughts exactly. Remember driving around in late March and April of 2020?
HypeBeastLastly, this is 100% political. Look at the distribution across states and rural areas.
You guys should probably stop politicizing it then...
let's not pretend that liberals didn't reject the lab leak hypothesis despite the evidence, the usage of hydroxychloroquine despite the evidence, and accepted the blatant manipulation of covid test data by the CDC during Trump's presidency. This whole thing is a Mexican stand-off of bullshit and it's so fuckin tiring. You guys regurgitate whatever Don Lemon, Steven Colbert, Jimmy Kimmel, Rachel Maddow, copy-paste any other liberal sycophant, says and think you're smart for doing so. You look down on people for disagreeing with you when YOU ARE JUST AS UNINFORMED. You don't know shit about science because if you did then you would understand that every theory presented is by its very nature FALSIFIABLE. Science does not deal in absolute truths. Liberals don't "believe in science" they believe in dogma spoon-fed to them by CNN.
SO maybe if you guys just shut the fuck up and stoped shaming people for 2 seconds conservatives would be more willing to take the vaccine.
