Yeah, like Caucasian Asian said, it does matter. It would be really inconvenient for a frequent traveler and the vials would have to be refrigerated if you were to take them with.
It's important to keep pace with the schedule they have for the shots, if you don't, they won't be effective and then you have to take a step back in the process. For example, I was in the section of treatment where I was getting shots once every other week and i missed one so they made me start getting them once a week again for a couple weeks.
So yeah it's quite the time commitment. If traveling would keep you from being able to follow the shot schedule then shots probably won't be an option for you.
But you should still maybe talk to a doctor about it, might find a way for it to workout for you.