I have a F-Stop Tilopa BC with the XL insert
-6x LP-e6 Batteries
-Canon 24-105 L
-70-200 2.8 L
- Rokinon 14 T 3.1
-Leica R- Cine Prime Set
-3 Red Bricks
-2x Canon Chargers
-1x Red Brick Charger
-Laptop and Card reader
-Random other stuff like ND and other filters/mounts....
Bottom line you can fit a lot in those things.
Problem i've found is that the quality on the outside of bag isn't super durable. I've had mine 4 months and its wearing down pretty well. Tears in multiple places, and I treat it like a baby. The best part is it always fits overhead even on regional planes.
Not sure on the water proofing but it seems to get pretty wet on the outside of it when it snows. Hasn't seemed to cause any dampness on the inner parts of the bag but it is a weakness I've found. Can take time to dry in crazy environments.