What video camera have you got? And have you got any still camera gear?
I had a LowePro Computrekker AW for a year, which was sick (although I only have still camera gear), and then went travelling so I got a LowePro Fastpack 250. Both of them hold a decent amount of gear (the Computrekker definitely holds more though) and a laptop. The Fastpack 250 doesn't have an all-weather cover which kinda sucks for the snow, but it does have an added pocket for non-camera related items - water bottle, small jumper, goggles, etc.
I've also heard DaKine Mission camera backpacks are pretty sick...so maybe it's worth checking them out too, but I know from experience LowePro make top notch stuff.