"Abruptly stopping Adderall after prolonged high dosage Adderall abuse results in extreme fatigue and mental depression. The most severe, though rare, Adderall side effects of Adderall abuse is psychosis. This Adderall abuse side effect is often clinically indistinguishable from schizophrenia.
Long-term methylphenidate and amphetamine use has also been linked to abnormalities in brain development, similar to those found with long-term cocaine use. Changes on the sleep EEG are also noted with Adderall abuse."
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