They degrade quickly. I went through 4 sets of cartridges, two sets of frames and have completely destroyed boots after 1 season. With all new stuff, the feeling is killer: tons of resistance with the springs cranked, zero play, and generally just a really positive feel. I now have about 10degrees of slop either direction on both bindings from wear on the second heels and the part of the binding that interfaces with them.
I had a mediocre experience with the 22designs NTN binding towards the end of last season. The binding seemed better than the rottafella freeride binding as far as support and build quality, but the demo skis they were mounted on were pretty terrifying when going fast, so I didn't get to test them quite to the degree I would have liked to.