so i live right in downtown Toronto, about 5 minutes away from yonge and dundas.
first of all safety? You wont have any problems unless you go looking for a fight, then you will get your ass handed to you. Don't be a jackass and nothing will happen.
Fake ID's... only a real idiot can not tell the difference, especially if you are planning to buy an ID downtown and use it downtown, seriously its barely worth your time. They look fake as shit, they work pretty well outside of the core but if you get passed a bouncer with it in toronto he is just letting you by, he knows its fake.
hotels... all are pretty central to everything, depends what you want to spend. the King eddie is amazing but $$
other than that they are all the same bed bug infested shit-holes, your only here for 2 days so save your money, go where is cheap.
as for clubs just go to the club district and just hop around till you find what your looking for.
if your young and looking for easy sex, brunswick house aka the brunny is among the easiest BUT they know fake ID's really well.
good luck to you buddy pm if you need more info
oh and fake id's just walk up yonge from dundas, there are a half dozen places that do them, one upstairs right by gould street (dunno if its still around) but they are hard to miss, all located between dundas and college st really.