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Message-ID: <022309Z20081993@anon.penet.fi>Newsgroups: alt.drugsFrom: an13187@anon.penet.fi (H-Man)Date: Fri, 20 Aug 1993 02:17:49 UTCSubject: VISINE to beat POT PISS-TESTS pt. 2I posted a message the other day about using VISINE to cause false-negativePOT PISS-TESTS. Well, I came down this morning and found that I was under aviaduct right near the university library, so I cleaned myself off a bit innearby FOUNTAIN and ambled in for some further research. Here is a reviewof two articles concerning false-negatives through SPECIMEN alteration with EYE-DROPS and a bit of speculation about how to use this information.Please respond with COMMENTS or CRITICISMS. |--########>-- H-Man --<########--|[1] "Adulterants Causing False Negative in Illicit Drug Testing" Clinical Chemistry, Nov 1988, Volume 34, Number 11, p 2333-2336. Stephen L. Mikkelsen and K. Owen Ash[2] "Mechanism of False-Negative Urine Cannabinoid Immunoassay Screens by Visine Eyedrops" Clinical Chemistry, Apr 1989, Volume 35, Number 4, p. 636-638. Stephen D. Pearson, K. Owen Ash, and Francis M. Urry[1] describes the effects of 8 different urine-additives (table salt,Visine, handsoap, Drano, bleach, vinegar, goldenseal tea, and lemon juice)on the outcome of various drug tests. Every effective additive exceptVisine leaves an easily detected telltale sign: Drano, bleach and vinegar change the specimen's pH outside the normal range; goldenseal tea causesthe specimen to turn brown; soap causes the specimen to become cloudy; andtable salt forces the sample's relative density out of the normal range.Lemon juice did not affect the tests. The abstract notes: "Visine was theonly adulterant not detected." [2] says that Visine does slightly reducethe urine sample's abaility to foam.Visine caused false negatives (EMIT d.a.u. assays) in the tests forbenzodiazepines and marijuana, but did not change the test results foramphetamines, barbituates, cocaine, or opiates. 125 mL / L was the amountof Visine used per amount of urine specimen with 122 ug / L of9-carboxy-THC in the sample.[2] focuses on the use of Visine to prevent pot metabolite detection. Hereis a table summarizing the effectiveness of varying concentrations ofVisine: Visine concentration (mL / L) : 0 10 20 50 100 200 300Apparent 9-carboxy-THC concentration (ug / L) : 100 52 43 47 35 85 87(Note the positive test cutoff value is 50 ug / L 9-carboxy-THC).The interesting thing to observe is the effectiveness of Visine as THCmetabolite masker decreases as its concentration goes up past a certainpoint. The same pattern occured with the TDx and Abuscreen assays (the TDxassay generated false negatives, but the Abuscreen assay's apparentmetabolite value fell only to 52 ug / L). The lesson to be learned is theoptimum amount of Visine to use is around 100 mL / L.The ingredients of Visine responsible for the blocking of the THC test aregiven as benzalkonium chloride (a preservative) and the borate buffer. Themechanisms of the borate buffer were not discussed, but "reducedavailability of 9-carboxy-THC in urine samples adulterated with Visine isdue in part to uptake of 9-carboxy-THC into benzalkonium chloride micelles."To use this information to your advantage, figure that the standard urinespecimen is 60 mL. At 100 mL / L Visine recommended, this means 6 mL ofVisine would cut the observed 9-carboxy-THC almost two-thirds. Visine comesin 15 mL and 30 mL bottles. For advice on how to add the adulterant, readAbbie Hoffman's book on piss-testing, _Steal this Urine Test_. Use of othermethods (such as diluting your urine by frequent water drinking) should beresearched. Adding adulterants can be risky and should be seen as alast-ditch effort if you're caught with your pants down, so to speak.-------------------------------------------------------------------------To find out more about the anon service, send mail to help@anon.penet.fi.Due to the double-blind, any mail replies to this message will be anonymized,and an anonymous id will be allocated automatically. You have been warned.Please report any problems, inappropriate use etc. to admin@anon.penet.fi.=============================================================================From: ACombs@utxvms.cc.utexas.edu (Alan B. Combs)Newsgroups: alt.drugsSubject: Re: VISINE to beat POT PISS-TESTS pt. 2Date: 24 Aug 1993 02:37:04 GMTMessage-ID: > > The ingredients of Visine responsible for the blocking of the THC test are> given as benzalkonium chloride (a preservative) and the borate buffer. The> mechanisms of the borate buffer were not discussed, but "reduced> availability of 9-carboxy-THC in urine samples adulterated with Visine is> due in part to uptake of 9-carboxy-THC into benzalkonium chloride micelles."> If this is the mechanism and it becomes established, there probably wouldbe a street market for Zephirin aqueous. It comes highly concentrated, andit is used as an antiseptic/surgical scrub, etc. The concentrate wouldhaveto be diluted appropriately. There are several less concentrated alcoholicsprays and tinctures. I suspect the alcohol would be quickly detected,however.
